1. 基因多态性与儿童非酒精性脂肪性肝病遗传易感性的分子机制研究
2. 营养流行病学研究(儿童肥胖/非酒精性脂肪性肝病,留守儿童营养素分析等)
1. 国家自然科学基金青年项目:81402741, 2015/01-2017/12,IRAK家族基因与HBV感染相关肝癌遗传易感性及其机制研究,23万,结题,主持。
2. 江苏省自然科学基金青年项目: BK20140904, 2014/06-2017/06,IRAK 家族基因遗传变异与HBV感染相关肝癌易感性的分子流行病学研究,20万,结题,主持。
3. 2020年录制《women’s reproductive and maternal health》课程。
4. 2021年澳门新葡澳京7906医学部《妇幼保健学》在线课程建设,9万,结题,主持。
5. 2022年度唐仲英青年学者项目:儿童NAFLD早期干预,16万,在研,主持。
1. Xing Y, Gao X, Li Q, Li X, Wang Y, Yang Y, Yang S, Lau PWC, Zeng Q, Wang H. Associations between exposure to ambient particulate matter and advanced liver fibrosis in Chinese MAFLD patients. J Hazard Mater. 2023 (IF=13.6,Q1)
2. Xing Y, Zhang P, Li X, Jin S, Xu M, Jia J, Wang HJ, Li L, Wang H. New predictive models and indices for screening MAFLD in school-aged overweight/obese children. Eur J Pediatr. 2023(IF=3.6, Q1).
3. 李雪莹; 宋洁云; 张萍萍; 王海俊; 王辉 ; TM6SF2 基因多态性与儿童非酒精性脂肪性肝病及血脂水平的关联, 现代预防医学, 2023., 50(6): 1117-1121
4. 张萍萍; 宋洁云; 王海俊; 王辉 ; PNPLA3 rs738409及UGT1A1 rs10929303基因多态性对儿童非酒精性脂肪性肝病的联合作用, 中华肝脏病杂志, 2023, 31(7): 723-728
5. Zhang PP, Song JY, Li L, Xu M, Wang H, Wang HJ. Associations between genetic variants of HSD17B13 and fasting plasma glucose in Chinese children. Nutr Metab Cardiovasc Dis. 2023. (IF=3.9, Q2)
6. Zou Z, Zhang Z, Lu C, Wang H. Comparison of time trends in the incidence of primary liver cancer between China and the United States: an age-period-cohort analysis of the Global Burden of Disease 2019. Chin Med J (Engl). 2022 Sep 5;135(17):2035-2042. doi: 10.1097/CM9.0000000000001980. (IF=6.1, Q1)
7. 张萍萍; 宋洁云; 王辉; 王海俊 ; 尿苷二磷酸葡萄糖醛酸转移酶1A1基因单核苷酸多态性与儿童青少年非酒精性脂肪肝及血脂水平的关联, 中国学校卫生, 2021, 42(09): 1388-1391+1395
8. Wang H, Wang Y, Song JY, Zhang PP, Song QY, Li CX, Li L, Wang HJ. Associations of genetic variants of lysophosphatidylcholine metabolic enzymes with levels of serum lipids. Pediatr Res. 2022 May;91(6):1595-1599. doi: 10.1038/s41390-021-01549-9. Epub 2021 May 2.(IF=3.6,Q1)
9. Wang H, El Maadidi S, Fischer J, Grabski E, Dickhöfer S, Klimosch S, Flannery SM, Filomena A, Wolz OO, Schneiderhan-Marra N, Löffler MW, Wiese M, Pichulik T, Müllhaupt B, Semela D, Dufour JF, Bochud PY, Bowie AG, Kalinke U, Berg T, Weber AN; East-German and Swiss Hepatitis C Virus Study Groups. A frequent hypofunctional IRAK2 variant is associated with reduced spontaneous hepatitis C virus clearance. Hepatology. 2015 Nov;62(5):1375-87. doi: 10.1002/hep.28105. Epub 2015 Sep 28. PMID: 26250868. (IF=14.0)
10. Wang H, Flannery SM, Dickhöfer S, Huhn S, George J, Kubarenko AV, Lascorz J, Bevier M, Willemsen J, Pichulik T, Schafmayer C, Binder M, Manoury B, Paludan SR, Alarcon-Riquelme M, Bowie AG, Försti A, Weber ANR. A coding IRAK2 protein variant compromises Toll-like receptor (TLR) signaling and is associated with colorectal cancer survival. J Biol Chem. 2014 Aug 15;289(33):23123-23131. doi: 10.1074/jbc.M113.492934. Epub 2014 Jun 19. (IF=4.8, Q2)